国外文献 > 1.轴承 > 1. 基础理论与机制 > 摩擦与润滑
关键词搜索：
| 标 题： |
A 3D printed biomimetic scaffold for cartilage regeneration with lubrication, load-bearing, and adhesive fixation properties
一种具有润滑、承重和粘附固定特性的3D打印仿生软骨再生支架 |
| 作 者： |
Wei, Pengyu
Ma, Yuanya
Qin, Kaiqi
Fan, Zengjie |
| 关键词： |
Biomimetic scaffold [仿生支架]
3D printing [ 3D打印]
Tissue engineering [ 组织工程]
Self-lubrication [ 自润滑]
Adhesive hydrogel [ 粘性水凝胶]
FRICTION [ 摩擦] |
| 出版年： |
2024 |
| 期刊名： |
Tribology International
摩擦学国际 |
| 年卷期： |
2024, vol.192 |
| 摘 要： |
Reconstructing the tri-layer structure of articular cartilage (AC) and replicating its functions pose significant challenges. In response, we propose a novel approach utilizing 3D printing technology to replicate and reconstruct the complex structure of AC. This is achieved by introducing three distinct functional hydrogels, each providing lubrication, load-bearing, and adhesive fixation functions. We have systematically characterized the structure, chemical composition, and function of each layer. The results demonstrate the effectiveness of the trilayer scaffold, which exhibits low friction, mechanical properties similar to natural AC, excellent adhesion capacity, and good biocompatibility. This study paves the way for innovation in the traditional methods of preparing biomimetic AC and has broad applications in osteochondral (OC) defect repair.
重建关节软骨（AC）的三层结构并复制其功能具有重大挑战。为此，我们提出一种利用3D打印技术来复制和重建AC复杂结构的新方法。该方法通过引入三种具有不同功能的水凝胶实现：分别提供润滑、承载和粘附固定作用。我们系统地表征了各层的结构、化学组成和功能。结果表明，这种三层支架具有低摩擦系数、与天然AC相似的力学性能、优异的黏附能力以及良好的生物相容性。本研究为传统仿生AC制备方法的创新提供了新路径，并在软骨缺损（OC）修复方面具有广泛的应用前景。 |
| 中文内容为网络AI翻译，专业术语未必准确，仅供参考。 |
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